Chronic recurrent multifocal osteomyelitis/ chronic nonbacterial osteomyelitis (CRMO/CNO)
Chronic recurrent multifocal osteomyelitis (CRMO) is an idiopathic inflammatory disorder of bone seen primarily in children and adolescents. Synonyms are subacute symmetric osteomyelitis, chronic symmetric osteomyelitis, chronic multifocal symmetric osteomyelitis, chronic multifocal cleidometaphyseal osteomyelitis, and tumorous osteomyelitis [1]. CRMO was first described by Giedion et al. in 1972 [2] (Chronic Recurrent Multifocal Osteomyelitis – A Rare Clinical Presentation and Review of Literature – PMC (nih.gov))
- Chronic Recurrent Multifocal Osteomyelitis (CRMO) – Resource Library – Sheffield Children’s NHS Foundation Trust (sheffieldchildrens.nhs.uk)
- BPSU study – Chronic recurrent multifocal osteomyelitis/ chronic nonbacterial osteomyelitis (CRMO/CNO) | RCPCH
- Sheffield Hospital Leaflet CRMO / CNO
- Chronic Recurrent Multifocal Osteomyelitis (CRMO) in children and young people. Information by Leeds Teaching Hospital
- INFORMATION LEAFLET FOR KIDS & TEENS – BPSU
- CRMO talk for family 2017-07-11
- Disease burden and social impact of pediatric chronic nonbacterial osteomyelitis from the patient and family perspective
Hospitals
Research
- EULAR 2019 abstracts CRMO
- Evolution of chronic recurrent multifocal osteomyelitis in a child shown by MRI
- Gain-of-function mutations in a member of the Src family kinases cause autoinflammatory bone disease in mice and humans
- Idiopathic CRMO and MEFV Gene Variant Alleles – Is There Any Relationship?
- Arthritis UK Pamidronate CRMO 2014
- Bisphosphonate treatment for children – Information for parents and carers
- Chronic non-bacterial osteomyelitis coexistent with familial Mediterranean fever
- Chronic non-bacterial osteomyelitis in the jaw
- Chronic non-bacterial osteomyelitis – A comparative study between children and adults
- Chronic Recurrent Multifocal Osteomyelitis – A Rare Clinical Presentation and Review of Literature
- CHRONI~4 Chronic recurrent multifocal osteomyelitis causing spinal cord compression
- Chronic recurrent multifocal osteomyelitis presenting as acute scoliosis – A case report and review of literature
