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Chronic recurrent multifocal osteomyelitis/ chronic nonbacterial osteomyelitis (CRMO/CNO)

Chronic recurrent multifocal osteomyelitis (CRMO) is an idiopathic inflammatory disorder of bone seen primarily in children and adolescents. Synonyms are subacute symmetric osteomyelitis, chronic symmetric osteomyelitis, chronic multifocal symmetric osteomyelitis, chronic multifocal cleidometaphyseal osteomyelitis, and tumorous osteomyelitis []. CRMO was first described by Giedion et al. in 1972 [] (Chronic Recurrent Multifocal Osteomyelitis – A Rare Clinical Presentation and Review of Literature – PMC (nih.gov))



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